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Lemairamin

Preclinical Research

Also known as: WGX-50, Raubasine analogue

Educational Content Only

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The FDA has not evaluated many of the peptides discussed here. Always consult a licensed healthcare provider before making any health decisions.

Overview

Lemairamin is a plant-derived alkaloid (isolated as WGX-50 from Evodia lepta) studied in the context of neuroprotection and neurological aging. Research in animal models has examined its potential to protect neurons from amyloid-beta toxicity and oxidative stress, with interest in Alzheimer's disease research.

Possible Uses

The following areas have been examined in research contexts. This does not constitute medical advice or imply proven efficacy in humans.

  • Cognitive Enhancement
  • Anti-Aging & Longevity
Mechanism of Action

Research suggests lemairamin may exert neuroprotective effects through antioxidant mechanisms, modulation of neuroinflammatory pathways, and potential inhibition of tau phosphorylation. Specific receptor binding targets are under investigation in preclinical settings.

Safety Notes

All research is preclinical. No human clinical trials. Not FDA-approved.

Research Profile

Half-Life

Not well characterized

Administration

oral (in animal studies)

Legal Status (US)

Research compound. Not FDA-approved.

13 indexed research passages

Categories
Cognitive & NeurologicalLongevity & Anti-Aging
Research Interest Areas
Cognitive EnhancementAnti-Aging & Longevity