TB-500
Preclinical ResearchAlso known as: Thymosin Beta-4, Tβ4
Educational Content Only
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The FDA has not evaluated many of the peptides discussed here. Always consult a licensed healthcare provider before making any health decisions.
TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4, a ubiquitous protein involved in actin sequestration and cell migration. Research in animal models has examined its potential roles in wound healing, angiogenesis, and cardiac repair.
The following areas have been examined in research contexts. This does not constitute medical advice or imply proven efficacy in humans.
- Muscle Recovery & Repair
- Cardiovascular Health
- Skin & Wound Healing
- Tendon & Joint Health
Thymosin Beta-4 regulates actin polymerization and cell motility. Research indicates it may promote angiogenesis, reduce inflammation, and support stem cell differentiation in injured tissues.
Primarily studied in animal models and some equine veterinary contexts. Limited human data available.
Selected peer-reviewed papers from research literature. These are educational references only and do not imply proven efficacy or safety in humans.
- Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro
Rahaman KA et al. (2024). Journal of Pharmaceutical and Biomedical Analysis.
- Thymosin β4 Promotes Dermal Healing
Goldstein AL. (2016). Annals of the New York Academy of Sciences.
- The regenerative peptide thymosin β4 accelerates the rate of dermal healing in preclinical animal models and in patients
Philp D, Goldstein AL, Kleinman HK. (2012). Wound Repair and Regeneration.
Want to learn more?
Ask Research Chat about TB-500Half-Life
~12 hours (estimated)
Administration
subcutaneous injection, intramuscular injection
Legal Status (US)
Research chemical in the US. Not approved for human use by the FDA. Banned by WADA for competitive athletes.
33 indexed research passages
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