Tesamorelin
FDA ApprovedAlso known as: Egrifta, TH9507
Educational Content Only
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The FDA has not evaluated many of the peptides discussed here. Always consult a licensed healthcare provider before making any health decisions.
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) consisting of the full 44-amino acid GHRH sequence with a trans-3-hexenoic acid modification to improve stability. It is FDA-approved for reduction of excess abdominal fat (lipodystrophy) in HIV-infected patients receiving antiretroviral therapy, and has been studied for cognitive function in aging.
The following areas have been examined in research contexts. This does not constitute medical advice or imply proven efficacy in humans.
- Growth Hormone Regulation
- Fat Loss & Metabolism
- Cognitive Enhancement
Binds to pituitary GHRH receptors and stimulates endogenous GH secretion through the natural pulsatile feedback axis, increasing IGF-1 and reducing visceral adipose tissue in HIV-associated lipodystrophy. Research also examines GH-mediated effects on cognition through IGF-1 signaling in the brain.
FDA-approved (Egrifta) for HIV-associated lipodystrophy. Side effects include injection site reactions, fluid retention, and carpal tunnel syndrome. May worsen insulin sensitivity.
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Ask Research Chat about TesamorelinHalf-Life
~26 minutes
Administration
subcutaneous injection
Legal Status (US)
FDA-approved prescription medication for HIV-associated lipodystrophy. Off-label use requires prescription.
39 indexed research passages
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