Androstadienone

Preclinical Research

Also known as: AND, 4,16-androstadien-3-one, androsta-4,16,-dien-3-one

Educational Content Only

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The FDA has not evaluated many of the peptides discussed here. Always consult a licensed healthcare provider before making any health decisions.

Overview

Androstadienone is an endogenous androgen derivative found in male sweat and axillary secretions, studied as a potential human chemosignal with effects on mood, social cognition, and neuroendocrine responses in females. Research has examined its ability to influence cortisol levels, attention to emotional stimuli, and social evaluation processes.

Possible Uses

The following areas have been examined in research contexts. This does not constitute medical advice or imply proven efficacy in humans.

Sexual Function
Cognitive Enhancement

Mechanism of Action

Proposed to act through the vomeronasal organ and/or main olfactory epithelium to trigger neuroendocrine responses including altered cortisol secretion and monoaminergic activity. The exact receptor targets and signaling pathways in human pheromone-like signaling remain under investigation.

Safety Notes

Endogenous compound found in human sweat. Very limited clinical pharmacology data. Not FDA-approved as a drug.

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Research Profile

Half-Life

Not well characterized

Administration

topical, intranasal (in research)

Legal Status (US)

Not FDA-approved as a drug. Used in research studies on human chemosignals.

227 indexed research passages

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