Selank
Phase II TrialsAlso known as: TP-7
Educational Content Only
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The FDA has not evaluated many of the peptides discussed here. Always consult a licensed healthcare provider before making any health decisions.
Selank is a synthetic heptapeptide analogue of the endogenous immunomodulatory peptide tuftsin, developed in Russia and studied for anxiolytic and nootropic effects. It has been approved as a drug in Russia.
The following areas have been examined in research contexts. This does not constitute medical advice or imply proven efficacy in humans.
- Immune Support
- Cognitive Enhancement
Research suggests Selank may modulate the expression of BDNF and serotonin metabolic systems, influence GABA-A receptor function, and exhibit immunomodulatory effects through enkephalin-related pathways.
Approved in Russia as a drug. Limited Western clinical trial data. Generally reported as well-tolerated in Russian studies.
Selected peer-reviewed papers from research literature. These are educational references only and do not imply proven efficacy or safety in humans.
- Predominance of Nootropic or Anxiolytic Effects of Selank, Semax, and Noopept Peptides Depending on the Route of Administration to BALB/c and С57BL/6 Mice
Vasileva EV et al. (2020). Neurochemical Journal.DOI: 10.1134/S1819712420030113
- Functional Connectomic Approach to Studying Selank and Semax Effects
Kasian AM et al. (2020). Neuropsychobiology.
Want to learn more?
Ask Research Chat about SelankHalf-Life
~2 minutes (short; nasal administration studied for longer effect)
Administration
intranasal, subcutaneous injection
Legal Status (US)
Research chemical in the US. Not FDA-approved.
32 indexed research passages
Related Peptides
Oxytocin is a nine-amino acid neuropeptide hormone produced in the hypothalamus and released by the posterior pituitary, studied extensively for its roles in social bonding, trust, maternal behavior, uterine contraction, and lactation. It is FDA-approved for obstetric indications and has been extensively studied in clinical contexts including autism spectrum disorder and social anxiety.
P21 is a short synthetic peptide derived from humanin with modifications intended to enhance potency and stability. Research has examined its potential roles in neuroprotection, cognitive function, and cellular survival signaling, particularly in the context of Alzheimer's disease models and age-related cognitive decline.
Tropisetron is a 5-HT3 receptor antagonist and alpha7 nicotinic acetylcholine receptor agonist approved in various countries for chemotherapy-induced nausea. Research has also examined its potential roles in pain management, fibromyalgia, and cognitive enhancement through its dual receptor pharmacology.
Lemairamin is a plant-derived alkaloid (isolated as WGX-50 from Evodia lepta) studied in the context of neuroprotection and neurological aging. Research in animal models has examined its potential to protect neurons from amyloid-beta toxicity and oxidative stress, with interest in Alzheimer's disease research.